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TriGene Advance

trigene advance invitro 340x420Distributed to the Medical/Healthcare sector by In Vitro Technologies.

 Available as:

      • 100ml RTU spray
      • 500ml RTU spray
      • 1 Litre RTU Refill
      • 2 Litre RTU Refill
      • 20 Litre RTU Refill
      • Wipes 100’s
      • Wipes 200’s
      • 250ml concentrate
      • 1 Litre concentrate
      • 2 Litre concentrate
      • 5 Litre concentrate
      • 20 Litre concentrate

receive free sample

Product Description

At the heart of the all-new TriGene Advance formula are the micro-emulsion particles (Nano particles) that enable the active ingredient molecules in the product to be carried rapidly through cell walls of micro-organisms.

Rapid penetration of cell walls by the powerful TriGene Advance disinfectant constituents ensures cell death is equally rapid. TriGene Advance works up to 70% quicker than conventional high level disinfectants and achieves apoptosis (cell death) rather than merely suspending activity as with conventional disinfectant products.

Because the Nano Particles can enter areas like microscopic fissures and crevices in hard surfaces, which have not hitherto been penetrable by conventional carrier systems, disinfectant actives are able to spread across a complete surface area, to perform a far more thorough anti pathogenic cleansing task than was previously possible.

The synergistic blend of TriGene Advance active ingredients produces the fastest acting and most efficient anti viral and sporicidal agent presently available in non-oxidising disinfectant technology.

Health and safety issues and product compatibility are of real importance to everyone. EA International encourages all users of chemical products to pay special attention to the advisory statements within Material Safety Data Sheets and on product labelling.

TriGene Advance is able to rely on lower levels of active ingredients than previously used, due to the formulation’s revolutionary method of delivering diluted disinfectant to the cells of micro-organisms. The simple prokaryotic cellular structure of micro-organisms provides little resistance to the active ingredients of TriGene Advance but the hugely more complex eukaryotic structure of the mammalian cell membrane means TriGene Advance is not cyto-toxic to mammalian tissue. Using the new system in the presence of human and animal skin is therefore of low risk. Notwithstanding this, instructions should always be followed carefully and gloves worn where advised.

Independent laboratory testing demonstrates no corrosion or deterioration of the following materials, even after long-term repeated immersions: Rubber compounds, Plastics, Fibreglass, Stainless Steel, Mild Steel, Aluminium, Copper, Brass and other materials found in clinical practice, in particular synthetic floors, instruments and devices.

Exposire Controls

  • Skin contact: Low risk – may degrease skin leading to dryness if excessive contact.
  • Eye contact: Low risk – may cause temporary discomfort.
  • Inhalation: Low risk – avoid inhalation of fine mist spray.
  • Inhalation (long term): Low risk – avoid inhalation of fine mist spray.
  • Ingestion: Low risk – substantial ingestion will cause discomfort to mouth and digestive tissues.

Physical and chemical properties

  • pH: 5.5 (approx)

Toxicological information

  • Human Studies: 4 hour and 20 hours patch tests have shown minor skin reddening but no harmful effects.

Transport information

  • No special conditions apply. Not dangerous.

Accidental release measures

  • Environmental precautions: Product is biodegradable under OECD conditions operational 6/1995.
  • Clean up method: Flush to drain with copious water or soak up onto inert material.

Ecological information

  • No known adverse effects from normal use.
  • The TriGene Advance formula fully meets the criteria of the European Biocides Regulations which came into force in 2007.
  • TriGene Advance has not been tested on animals to secure its supporting data.

Because required results are generated with higher dilutions of TriGene Advance , greater economies are effected at point of use. For example, an acceptable ‘kill’ rate for Parvo virus is widely accepted as 99.99% (log 4) in a thirty minute exposure. This corresponds to the test protocol used by the UK Animal Health Institute and to the protocol accepted world-wide under EPA conditions.

TriGene Advance produces a 99.999+% (log 5+) kill rate in Parvo under the EPA protocol at a dilution of 1:100 (1 part disinfectant in 100 parts water).

Users of disinfectants in human health/laboratory and life science environments require maximum protection from the use of a disinfectant with proven independent microbiological test certification. Many disinfectants require strong dilutions for critical risk areas like Parvovirus or TB, yet are marketed for use at much weaker dilutions for “broad spectrum activity”, putting both the organisation and patients at risk of cross infection.

TriGene Advance users can rely on one dilution (1:100) for broad spectrum activity (supported by independent testing) in high risk conditions against viruses, mycobacteria, fungi and bacterial organisms and another for economic general purpose disinfection (1:200) in intermediate risk areas.

Worktops/equipment

  • Wash down all surfaces with TriGene Advance at 1:100 and dry with paper towel or allow to dry naturally. Alternatively use TriGene Advance in RTU (ready to use) trigger spray and wipe excess moisture with paper towel and allow to dry.
  • TriGene Advance wipes can also be used to wipe surfaces.

Device immersion

  • Non-critical devices can be soaked in TriGene Advance if required during a period of high risk in a solution of 1:100 for 20 mins.
  • Fabrics can be soaked in a solution of TriGene Advance at 1:100 for 10 minute. They can also be washed in an automatic washing machine using 50ml per 4kg load during a normal washing cycle.

Floor, walls

  • For general washing of floors and surfaces use TriGene Advance at 1:200. Use with mop and bucket on floors, remove excess moisture and allow to dry.
  • Wash other surfaces, rince where necessary and remove excess moisture and allow to dry.

Fogging and pressure washing

  • Where applicable TriGene Advance can be used in pressure washing machines at a dilution of 1:200, rinsed and allowed to dry.
  • Where aerial fogging is required, non-fragranced product should be used at a dilution of 1:200. masks should be worn and the area vacated until dry.

Wipes

  • TriGene Advance wipes, impregnated at 1:10 are recommended for disinfection of probes, transducers, incubators and for machines used for x-ray, mammography, radiology, etc.
  • As well as other sealed medical devices.

A Selection of Efficacy Test Results Held on File

Methodology Organism Log Reduction Laboratory Dilution Clean/dirty conditions or low level soiling/high level soiling Time
Mycobactericidal            
P2, S1 EN 14348 Mycobacterium avium >2.79 Abbott Analytical 1:100 dirty 30 mins
  Mycobacterium bovis 1.39 Abbott Analytical 1:100 dirty 30 mins
  Mycobacterium fortuitum <7.14 Abbott Analytical 1:100 dirty 30 mins
  Mycobacterium terrae (TB) >5.79 Abbott Analytical 1:100 dirty 30 mins
Virucidal            
P2, S1 EN 14476 Canine parvovirus 5.67 Blutest 1:100 clean 30 mins
  Adenovirus T5 4.16 Blutest 1:100 clean 30 mins
  Feline Calicivirus 5.50 Blutest 1:100 clean 30 mins
U.S. EPA Adenovirus T5 >5 ATS 1:100 5% FBS 30 mins
  Hepatitis B >4.21 ATS 1:100 N/A 30 mins
  Human Immunodeficiency Virus T1 >4.5 ATS 1:100 5% FBS 30 mins
  Human Coronavirus >4.751 ATS 1:100 1% FBS 30 mins
Fungicidal / Yeasticidal            
P2, S2 EN 13697 Candida albicans >3.4 MGS 1:100 dirty 5 mins
P2, S1 EN 13624 Candida albicans >5.06 MGS 1:100 clean 5 mins
Bactericidal            
P2,S2 EN 14561 Enterococcus hirae 5.24 MGS 1:100 clean 5 mins
P2, S1 EN 1656 Enterococcus hirae >5.08 MGS 1:200 low level soiling 5 mins
  Staphylococcus aureus >5.12 MGS 1:200 low level soiling 5 mins
  Campylobacter jejuni >5.36 MGS 1:200 low level soiling 5 mins
  Stenotrophomonas maltophilia >5.53 MGS 1:200 low level soiling 5 mins
  Methicillin-resistant Staphylococcus pseudimintermedius >5.44 MGS 1:200 low level soiling 5 mins
  Proteus vulgaris >5.16 MGS 1:200 low level soiling 5 mins
  Streptococcus equi >5.34 MGS 1:200 low level soiling 5 mins
  Rhodococcus equi >5.40 MGS 1:100 low level soiling 5 mins
  Bordatella bronchiseptica 4.15 MGS 1:100 low level soiling 5 mins
P2, S1 EN 13727 Methicillin-resistant Staphylococcus aureus >5.34 MGS 1:200 clean 5 mins
  Enterococcus hirae >5.0 Eclipse 1:200 clean and dirty 5 mins
  Staphylococcus aureus >5.0 Eclipse 1:200 clean and dirty 5 mins
  Pseudomonas aeruginosa >5.0 Eclipse 1:200 clean and dirty 5 mins
P2, S1 EN 1276 Enterococcus hirae >5.0 Eclipse 1:200 clean and dirty 5 mins
  Staphylococcus aureus >5.0 Eclipse 1:200 clean and dirty 5 mins
  Pseudomonas aeruginosa >5.0 Eclipse 1:200 clean and dirty 5 mins
  Escherichia coli >5.0 Eclipse 1:200 clean and dirty 5 mins
P2, S1 EN 1650 Microsporum audouinii >4.3 University of Huddersfield 1:100 clean 30 mins
  Trichophyton tonsurans >4.1 University of Huddersfield 1:100 clean 60 mins
26.04.2017